Since I work as a fulltime illustrator, I find extremally frustrating when I spend months, if not years, developing a nice art style just so someone can come as says that "It looks like anime", when it clearly has nothing to do with it.
I'm not against people who actually draw in anime style, heck, I even had my anime phase, which helped me a lot with human anatomy.
It's just that I find it EXTREMELY FRUSTRATING when someone assumes that everything is "Anime Style"